Cardiorespiratory fitness and the incidence of type 2 diabetes: Prospective study of Japanese men

Susumu S. Sawada, I. Min Lee, Takashi Muto, Kazuko Matuszaki, Steven N. Blair

研究成果: Article査読

106 被引用数 (Scopus)

抄録

OBJECTIVE - To investigate the association between cardiorespiratory fitness and the incidence of type 2 diabetes among Japanese men. RESEARCH DESIGN AND METHODS - This prospective cohort study was conducted in 4,747 nondiabetic Japanese men, aged 20-40 years at baseline, enrolled in 1985 with follow-up to June 1999. Cardiorespiratory fitness was measured using a cycle ergometer test, and VO2max was estimated. During a 14-year follow-up, 280 men developed type 2 diabetes. RESULTS - The age-adjusted relative risks of developing type 2 diabetes across quartiles of cardiorespiratory fitness (lowest to highest) were 1.0 (referent), 0.56 (95% CI 0.42-0.75), 0.35 (0.25-0.50), and 0.25 (0.17-0.37) (for trend, P < 0.001). After further adjustment for BMI, systolic blood pressure, family history of diabetes, smoking status, and alcohol intake, the association between type 2 diabetes risk and cardiorespiratory fitness was attenuated but remained significant (1.0, 0.78, 0.63, and 0.56, respectively; for trend, P = 0.001). CONCLUSIONS - These results indicate that a low cardiorespiratory fitness level is an important risk factor for incidence of type 2 diabetes among Japanese men.

本文言語English
ページ(範囲)2918-2922
ページ数5
ジャーナルDiabetes care
26
10
DOI
出版ステータスPublished - 2003 10 1
外部発表はい

ASJC Scopus subject areas

  • 内科学
  • 内分泌学、糖尿病および代謝内科学
  • 高度および特殊看護

フィンガープリント

「Cardiorespiratory fitness and the incidence of type 2 diabetes: Prospective study of Japanese men」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル