Cardiorespiratory fitness, body mass index, and cancer mortality: A cohort study of Japanese men

Susumu S. Sawada, I. Min Lee, Hisashi Naito, Ryo Kakigi, Sataro Goto, Masaaki Kanazawa, Takashi Okamoto, Koji Tsukamoto, Takashi Muto, Hiroaki Tanaka, Steven N. Blair

研究成果: Article査読

24 被引用数 (Scopus)

抄録

Background: The aim of this study is to investigate the independent and joint effects of cardiorespiratory fitnes (CRF) and body mass index (BMI) on cancer mortality in a low body mass index population Methods: We evaluated CRF and BMI in relation to cancer mortality in 8760 Japanese men. The median BMI wa 22.6 kg/m2 (IQR: 21.0-24.3). The mean follow-up period was more than 20 years. Hazard ratios and 95% CI wer obtained using a Cox proportional hazards model while adjusting for several confounding factors Results: Using the 2nd tertile of BMI (21.6-23.6 kg/m2) as reference, hazard ratios and 95% CI for the lowest tertil of BMI (18.5-21.5) were 1.26 (0.87-1.81), and 0.92 (0.64-1.34) for the highest tertile (23.7-37.4). Using the lowes tertile of CRF as reference, hazard ratios and 95% CIs for 2nd and highest tertiles of CRF were 0.78 (0.55-1.10) an 0.59 (0.40-0.88). We further calculated hazard ratios according to groups of men cross-Tabulated by tertiles of CR and BMI. Among men in the second tertile of BMI, those belonging to the lowest CRF tertile had a 53% lower ris of cancer mortality compared to those in the lowest CRF tertile (hazard ratio: 0.47, 95% CI: 0.23-0.97). Among thos in the highest BMI tertile, the corresponding hazard ratio was 0.54 (0.25-1.17) Conclusion: These results suggest that high CRF is associated with lower cancer mortality in a Japanese populatio of men with low average BMI.

本文言語English
論文番号1012
ジャーナルBMC Public Health
14
1
DOI
出版ステータスPublished - 2014
外部発表はい

ASJC Scopus subject areas

  • 公衆衛生学、環境および労働衛生

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