Cerebral amyloid angiopathy as a cause of subarachnoid hemorrhage

Toshio Ohshima, Toyoshi Endo, Hideaki Nukui, Shu Ichi Ikeda, David Allsop, Toshimasa Onaya

研究成果: Article査読

34 被引用数 (Scopus)

抄録

Cerebral amyloid angiopathy is a pathologic condition characterized by the deposition of amyloid in the walls of small vessels in the cerebral cortex and meninges. Intracerebral hemorrhage is common in persons with this condition, but pure subarachnoid or subdural hemorrhage is rarely seen. Recently, the existence of two types of amyloid proteins related to cerebral amyloid angiopathy, ß protein and cystatin C, has been reported, and Immunohis-tochemical methods using antisera to these proteins have become available. We describe a patient with fatal subarachnoid hemorrhage presumably caused by ß protein-type cerebral amyloid angiopathy, which was demonstrated immunohistochemicaliy by using a monoclonal antibody to a synthetic peptide corresponding to residues 8-17 of ß protein. We suggest that ft protein-type cerebral amyloid angiopathy is a possible etiologic factor in subarachnoid hemorrhage of unknown cause.

本文言語English
ページ(範囲)480-483
ページ数4
ジャーナルStroke
21
3
DOI
出版ステータスPublished - 1990 3
外部発表はい

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialised Nursing

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