Cerebral blood flow and neurovascular coupling during static exercise

Yuji Yamaguchi, Hideaki Kashima, Yoshiyuki Fukuba, Naoyuki Hayashi*

*この研究の対応する著者

研究成果: Article査読

10 被引用数 (Scopus)

抄録

The effect of static exercise on neurovascular coupling (NVC) was investigated by measuring the blood flow velocity in the posterior cerebral artery (PCAv) during 2-min static handgrip exercises (HG) at 30 % of the maximum voluntary contraction in 17 healthy males. NVC was estimated as the relative change in PCAv from eye closing to a peak response to looking at a reversed checkerboard. The conductance index (CI) was calculated by dividing PCAv by the mean arterial pressure (MAP). HG significantly increased PCAv from the resting baseline, with an increase in MAP and a reduction in CI, whereas NVC did not differ significantly between the resting and HG. Compared to the resting baseline, HG significantly increased the pressor response to visual stimulation by 5.6 ± 1.1 (mean ± SE) mmHg, while the CI response was significantly inhibited by -7.0 ± 1.5 %. These results indicate that NVC was maintained during HG via contributions from both the pressor response and vasodilatation.

本文言語English
ページ(範囲)195-201
ページ数7
ジャーナルJournal of Physiological Sciences
64
3
DOI
出版ステータスPublished - 2014 5月
外部発表はい

ASJC Scopus subject areas

  • 生理学

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