Changes in amygdaloid afterdischarges and kindling effect following olfactory bulbectomy in the rat

Shigenori Watanabe, Hiroshi Nakanishi, Shigenobu Shibata, Showa Ueki

研究成果: Article

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Changes in the thresholds for afterdischarges and the formation of kindling effect in the medial amygdala following olfactory bulbectomy were investigated in the rat with chronic electrode implants. The threshold for afterdischarges in the amygdala of the olfactory bulbectomized rat (OB rat) was significantly decreased on day 4 after olfactory bulbectomy, however, no significant difference was found between OB and sham operated rats on days 7, 14 and 21 since the threshold in the sham group was also decreased at these periods after the surgery. The formation of kindling effect was remarkably accelerated in the OB rats. In this case, the number of days required to reach the stage 1 (Racine's classification) was significantly shortened. These results suggest that the activity of the medial amygdaloid nucleus is increased following olfactory bulbectomy.

元の言語English
ページ(範囲)687-692
ページ数6
ジャーナルPhysiology and Behavior
28
発行部数4
DOI
出版物ステータスPublished - 1982 4

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ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

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