Changes in male brain responses to emotional faces from adolescence to middle age

Quinton Deeley*, Eileen M. Daly, Rayna Azuma, Simon Surguladze, Vincent Giampietro, Michael J. Brammer, Brian Hallahan, Robin I.M. Dunbar, Mary L. Phillips, Declan G.M. Murphy

*この研究の対応する著者

研究成果査読

43 被引用数 (Scopus)

抄録

Facial emotion perception is fundamental to human social behaviour, and changes with age. Nevertheless, age-related differences in the relative activation of components of emotion processing networks are poorly understood. Thus we measured brain activity with event-related fMRI in 40 right handed healthy male controls, age range 8-50 years, during implicit processing of fearful, disgusted, and a control condition of neutral facial expressions. There was a significant negative correlation between increasing age and neural response to fearful and disgusted expressions in dorsomedial prefrontal cortex (BA 10), and middle frontal gyri (BA 6). Hence, in healthy subjects, the functional anatomy of facial emotion processing is not 'hard-wired', but undergoes progressive change into adulthood. Possible explanations for the age-related changes in dorsomedial and middle frontal cortical activity may include a reduction in the attentional demands of appraising facial expressions as perceptual skill increases, or changes in processing the self-relevance of facial expressions during social and cognitive development.

本文言語English
ページ(範囲)389-397
ページ数9
ジャーナルNeuroImage
40
1
DOI
出版ステータスPublished - 2008 3 1
外部発表はい

ASJC Scopus subject areas

  • 神経学
  • 認知神経科学

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