Characterization of hybridization on diamond solution-gate field-effect transistors for detecting single mismatched oligonucleotides

Jung Hoon Yang, Shouma Kuga, Kwang Soup Song, Hiroshi Kawarada

    研究成果: Article

    4 引用 (Scopus)

    抄録

    Using diamond field-effect transistors (FETs) operated in electrolyte solution (solution-gate FETs; SGFETs), a label-free charge detection method between complementary and single mismatched target oligonucleotides is proposed. The probe oligonucleotides immobilized at the activated carboxyl groups of carboxylic aromatic compounds (CACs) on the previously formed amino groups of the diamond surface. The high performance of the diamond surface for oligonucleotides detection was studied with respect to selectivity, sensitivity, and reproducibility of the diamond SGFETs.

    元の言語English
    ページ(範囲)1180011-1180013
    ページ数3
    ジャーナルApplied Physics Express
    1
    発行部数11
    DOI
    出版物ステータスPublished - 2008 11

    Fingerprint

    Gates (transistor)
    oligonucleotides
    Oligonucleotides
    Diamonds
    field effect transistors
    diamonds
    aromatic compounds
    Aromatic compounds
    carboxyl group
    Field effect transistors
    Labels
    selectivity
    Electrolytes
    electrolytes
    probes
    sensitivity

    ASJC Scopus subject areas

    • Engineering(all)
    • Physics and Astronomy(all)

    これを引用

    Characterization of hybridization on diamond solution-gate field-effect transistors for detecting single mismatched oligonucleotides. / Yang, Jung Hoon; Kuga, Shouma; Song, Kwang Soup; Kawarada, Hiroshi.

    :: Applied Physics Express, 巻 1, 番号 11, 11.2008, p. 1180011-1180013.

    研究成果: Article

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