Characterization of poly(N-isopropylacrylamide) gel grafted polydimethylsiloxane as temperature-responsive cell culture substrate

Yoshikatsu Akiyama; Miki Matsuyama; Naoya Takeda; Masayuki Yamato; Teruo Okano

doi:10.1109/MHS.2016.7824169

Characterization of poly(N-isopropylacrylamide) gel grafted polydimethylsiloxane as temperature-responsive cell culture substrate

Yoshikatsu Akiyama^*, Miki Matsuyama, Naoya Takeda, Masayuki Yamato, Teruo Okano

^*この研究の対応する著者

研究成果: Conference contribution

抄録

Poly(N-isopropylacrylamide) (PIPAAm) hydrogel modified poly(dimethylsiloxane) (PDMS) surface (PIPAAm-PDMS) was prepared as a new temperature-responsive cell culture surface by using electron beam (EB) irradiation method. PIPAAm-PDMS surface properties at unstretched and stretched states were characterized by using various analytical method. As the result, we found that PIPAAm-PDMS surface properties as well as thickness of the grafted PIPAAm gel were altered by applied uniaxial mechanical stretching stress. The mechanical stress can affect the degree of hydration of grafted PIPAAm chains.

本文言語	English
ホスト出版物のタイトル	2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016
出版社	Institute of Electrical and Electronics Engineers Inc.
ISBN（電子版）	9781509027842
DOI	https://doi.org/10.1109/MHS.2016.7824169
出版ステータス	Published - 2017 1月 18
外部発表	はい
イベント	27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016 - Nagoya, Japan 継続期間: 2016 11月 28 → 2016 11月 30

Other

Other	27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016
国/地域	Japan
City	Nagoya
Period	16/11/28 → 16/11/30

ASJC Scopus subject areas

医学（その他）
生体医工学
機械工学
人間とコンピュータの相互作用
器械工学
コンピュータサイエンスの応用
バイオテクノロジー
人工知能

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

文献へのアクセス

10.1109/MHS.2016.7824169

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引用スタイル

Akiyama, Y., Matsuyama, M., Takeda, N., Yamato, M., & Okano, T. (2017). Characterization of poly(N-isopropylacrylamide) gel grafted polydimethylsiloxane as temperature-responsive cell culture substrate. In 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016 [7824169] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MHS.2016.7824169

Characterization of poly(N-isopropylacrylamide) gel grafted polydimethylsiloxane as temperature-responsive cell culture substrate. / Akiyama, Yoshikatsu; Matsuyama, Miki; Takeda, Naoya その他.

2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016. Institute of Electrical and Electronics Engineers Inc., 2017. 7824169.

研究成果: Conference contribution

Akiyama, Y, Matsuyama, M, Takeda, N, Yamato, M & Okano, T 2017, Characterization of poly(N-isopropylacrylamide) gel grafted polydimethylsiloxane as temperature-responsive cell culture substrate. in 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016., 7824169, Institute of Electrical and Electronics Engineers Inc., 27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016, Nagoya, Japan, 16/11/28. https://doi.org/10.1109/MHS.2016.7824169

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abstract = "Poly(N-isopropylacrylamide) (PIPAAm) hydrogel modified poly(dimethylsiloxane) (PDMS) surface (PIPAAm-PDMS) was prepared as a new temperature-responsive cell culture surface by using electron beam (EB) irradiation method. PIPAAm-PDMS surface properties at unstretched and stretched states were characterized by using various analytical method. As the result, we found that PIPAAm-PDMS surface properties as well as thickness of the grafted PIPAAm gel were altered by applied uniaxial mechanical stretching stress. The mechanical stress can affect the degree of hydration of grafted PIPAAm chains.",

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