Chicken red-sensitive cone visual pigment retains a binding domain for transducin

Yoshitaka Fukada, Toshiyuki Okano, Igor D. Artamonov, Tôru Yoshizawa*

*この研究の対応する著者

研究成果: Article査読

21 被引用数 (Scopus)

抄録

Iodopsin (a red-sensitive cone visual pigment) and rhodopsin (a rod pigment) were isolated from chicken retina. They were separately reconstituted into phosphatidylcholine liposomes and then mixed with rod transducin (Tα and Tβγ) purified from bovine retina. Iodopsin enhanced, only when irradiated, the binding of GppNHp to Tα to a similar extent to irradiated rhodopsin. Furthermore, the binding of GppNHp to Tα in the presence of a photobleaching intermediate of iodopsin preferably required Tβγ-2 rather than Tβγ-1, which is very similar in profile to that in the presence of the intermediate of rhodopsin (J. Biol. Chem., in press). These results indicate that the binding domain for transducin in iodopsin should closely resemble that in rhodopsin.

本文言語English
ページ(範囲)69-72
ページ数4
ジャーナルFEBS Letters
246
1-2
DOI
出版ステータスPublished - 1989 3 27
外部発表はい

ASJC Scopus subject areas

  • 生物理学
  • 構造生物学
  • 生化学
  • 分子生物学
  • 遺伝学
  • 細胞生物学

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