Cloning and characterization of the promoter of murine cytohesin-1 gene

Nobuhito Goda; Akito Tanoue; Shintaro Kikuchi; Gozoh Tsujimoto

doi:10.1016/S0167-4781(00)00160-3

Cloning and characterization of the promoter of murine cytohesin-1 gene

Nobuhito Goda, Akito Tanoue, Shintaro Kikuchi, Gozoh Tsujimoto

研究成果: Article

5 引用（Scopus）

抜粋

Mouse cytohesin-1 (CTH-1) is a guanine nucleotide exchange factor, specific for ADP ribosylation factors. The CTH-1 gene promoter was characterized by deletion mapping and mutational analysis. The region between -101 and -38 relative to the transcription start site showed the essential promoter activity when transfected into both NIH3T3 and COS7 cells. The nucleotides of the core promoter region contain three tandem GC boxes, which can offer potential binding sites for the ubiquitous transcription factor Sp- 1 family. Mutational analysis revealed that these tandem GC boxes are indispensable for activation of the gene transcription. (C) 2000 Elsevier Science B.V.

元の言語	English
ページ（範囲）	195-199
ページ数	5
ジャーナル	Biochimica et Biophysica Acta - Gene Structure and Expression
巻	1493
発行部数	1-2
DOI	https://doi.org/10.1016/S0167-4781(00)00160-3
出版物ステータス	Published - 2000 9 7
外部発表	Yes

ASJC Scopus subject areas

Structural Biology
Biophysics
Biochemistry
Genetics

文献にアクセス

10.1016/S0167-4781(00)00160-3

フィンガープリント Cloning and characterization of the promoter of murine cytohesin-1 gene' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

これを引用

Goda, N., Tanoue, A., Kikuchi, S., & Tsujimoto, G. (2000). Cloning and characterization of the promoter of murine cytohesin-1 gene. Biochimica et Biophysica Acta - Gene Structure and Expression, 1493(1-2), 195-199. https://doi.org/10.1016/S0167-4781(00)00160-3

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