Comprehensive study of microgel electrode for on-chip electrophoretic cell sorting

Akihiro Hattori*, Kenji Yasuda

*この研究の対応する著者

研究成果: Article査読

11 被引用数 (Scopus)

抄録

We have developed an on-chip cell sorting system and microgel electrode for applying electrostatic force in microfluidic pathways in the chip. The advantages of agarose electrodes are 1) current-driven electrostatic force generation, 2) stability against pH change and chemicals, and 3) no bubble formation caused by electrolysis. We examined the carrier ion type and concentration dependence of microgel electrode impedance, and found that CoCl2 has less than 1/10 of the impedance from NaCl, and the reduction of the impedance of NaCl gel electrode was plateaued at 0.5 M. The structure control of the microgel electrode exploiting the surface tension of sol-state agarose was also introduced. The addition of 1% (w/v) trehalose into the microgel electrode allowed the frozen storage of the microgel electrode chip. The experimental results demonstrate the potential of our system and microgel electrode for practical applications in microfluidic chips.

本文言語English
ページ(範囲)06GM041-06GM044
ジャーナルJapanese journal of applied physics
49
6 PART 2
DOI
出版ステータスPublished - 2010 6
外部発表はい

ASJC Scopus subject areas

  • 工学(全般)
  • 物理学および天文学(全般)

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