@article{588e9086d53a43e3a14962a3cf6a4ec3,
title = "Computational approaches for alternative and transient secondary structures of ribonucleic acids",
abstract = "Transient and alternative structures of ribonucleic acids (RNAs) play essential roles in various regulatory processes, such as translation regulation in living cells. Because experimental analyses for RNA structures are difficult and time-consuming, computational approaches based on RNA secondary structures are promising. In this article, we review computational methods for detecting and analyzing transient/alternative secondary structures of RNAs, including static approaches based on probabilistic distributions of RNA secondary structures and dynamic approaches such as kinetic folding and folding pathway predictions.",
keywords = "Alternative/transient structures, Folding pathway, Kinetic folding, Probability distribution of secondary structures, RNA secondary structures, Riboswitch",
author = "Tsukasa Fukunaga and Michiaki Hamada",
note = "Funding Information: This work was supported by the Ministry of Education, Culture, Sports, Science and Technology [KAKENHI grant JP17H05605 to T.F. and JP17K20032, JP16H05879, JP16H01318 and JP16H02484 to M.H.]. Publisher Copyright: {\textcopyright} The Author(s) 2019. Published by Oxford University Press. All rights reserved.",
year = "2018",
month = jun,
day = "20",
doi = "10.1093/bfgp/ely042",
language = "English",
volume = "18",
pages = "182--191",
journal = "Briefings in Functional Genomics",
issn = "2041-2649",
publisher = "Oxford University Press",
number = "3",
}