dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project

the Tohoku Medical Megabank Project Study Group

研究成果: Article査読

1 被引用数 (Scopus)

抄録

To reveal gene-environment interactions underlying common diseases and estimate the risk for common diseases, the Tohoku Medical Megabank (TMM) project has conducted prospective cohort studies and genomic and multiomics analyses. To establish an integrated biobank, we developed an integrated database called “dbTMM” that incorporates both the individual cohort/clinical data and the genome/multiomics data of 157,191 participants in the Tohoku Medical Megabank project. To our knowledge, dbTMM is the first database to store individual whole-genome data on a variant-by-variant basis as well as cohort/clinical data for over one hundred thousand participants in a prospective cohort study. dbTMM enables us to stratify our cohort by both genome-wide genetic factors and environmental factors, and it provides a research and development platform that enables prospective analysis of large-scale data from genome cohorts.

本文言語English
論文番号44
ジャーナルHuman Genome Variation
8
1
DOI
出版ステータスPublished - 2021 12月
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 分子生物学
  • 遺伝学

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