Decarbonylative Synthesis of Aryl Nitriles from Aromatic Esters and Organocyanides by a Nickel Catalyst

Keiichiro Iizumi, Miki B. Kurosawa, Ryota Isshiki, Kei Muto, Junichiro Yamaguchi*

*この研究の対応する著者

研究成果査読

3 被引用数 (Scopus)

抄録

A decarbonylative cyanation of aromatic esters with aminoacetonitriles in the presence of a nickel catalyst was developed. The key to this reaction was the use of a thiophene-based diphosphine ligand, dcypt, permitting the synthesis of aryl nitrile without the generation of stoichiometric metal- or halogen-containing chemical wastes. A wide range of aromatic esters, including hetarenes and pharmaceutical molecules, can be converted into aryl nitriles.

本文言語English
論文番号st-2020-k0464-c
ページ(範囲)1555-1559
ページ数5
ジャーナルSynlett
32
15
DOI
出版ステータスPublished - 2021 9 16

ASJC Scopus subject areas

  • 有機化学

フィンガープリント

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