Decreased serum brain-derived neurotrophic factor in trained men

Yu Nofuji, Masataka Suwa, Yoshihiko Moriyama, Hiroshi Nakano, Atsushi Ichimiya, Reiko Nishichi, Haruka Sasaki, Zsolt Radak, Shuzo Kumagai*

*この研究の対応する著者

研究成果: Article査読

77 被引用数 (Scopus)

抄録

The purpose of this study was to clarify the effect of physical activity on the level of serum brain-derived neurotrophic factor (BDNF). The serum BDNF level in trained men who have participated in regular sport activity (n = 12) was compared to that in sedentary subjects (n = 14). The physical activity levels expressed as total energy expenditure, move-related energy expenditure and walking count in the trained were significantly higher than those in the sedentary. The serum BDNF level in the trained men was found to be lower than that in the sedentary (19.54 ± 4.53 ng/ml vs. 23.63 ± 2.94 ng/ml, respectively, P < 0.01). The serum BDNF level showed a significant negative correlation with daily total energy expenditure (r = -0.507, P < 0.05), movement-related energy expenditure (r = -0.503, P < 0.05), and walking count (r = -0.480, P < 0.05). These results may suggest that vigorous habitual physical activity decrease the serum BDNF level.

本文言語English
ページ(範囲)29-32
ページ数4
ジャーナルNeuroscience Letters
437
1
DOI
出版ステータスPublished - 2008 5月 23
外部発表はい

ASJC Scopus subject areas

  • 神経科学(全般)

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