Dependence of protein binding capacity of dimethylamino-γ-butyric-acid (DMGABA)-immobilized porous membrane on composition of solvent used for DMGABA immobilization

Akio Iwanade*, Daisuke Umeno, Kyoichi Saito, Takanobu Sugo

*この研究の対応する著者

研究成果: Article査読

3 被引用数 (Scopus)

抄録

Dimethylamino-γ-butyric acid (DMGABA) as an ampholite was reacted with the epoxy group of the poly-glycidyl methacrylate chain grafted onto the pore surface of a porous hollow-fiber polyethylene membrane by radiation-induced graft polymerization. DMGABA was dissolved in a mixture of dioxane and water at various dioxane volume fractions, defined by dividing the dioxane volume by the total volume. The equilibrium binding capacity (EBC) of the DMGABA-immobilized porous hollow-fiber membrane for lysozyme was evaluated in the permeation mode. The EBC was varied from a 1/50-fold monolayer binding capacity to a 10-fold monolayer binding capacity by controlling the composition of the solvent used for DMGABA immobilization and the molar conversion of the epoxy group into the DMGABA group.

本文言語English
ページ(範囲)53-58
ページ数6
ジャーナルRadiation Physics and Chemistry
87
DOI
出版ステータスPublished - 2013 6
外部発表はい

ASJC Scopus subject areas

  • 放射線

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