Designs for size-exclusion separation of macromolecules by densely-engineered mesofilters

Sherif A. El-Safty

    研究成果: Article

    38 引用 (Scopus)

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    This critical review reports on the up-to-date development designs of mesofilters for molecular sieving of macromolecules. Tight mesoporous silica nanotubes (NTs) provide a promising candidate as a filter for the size-exclusion separation of large quantities of macromolecules within a short period. First, we focus on the formation of the mesoporous structures inside anodic alumina membrane (AAM) using nanolinker approaches. Second, we discuss the systematic design of the robust mesofilters based on densely-engineered mesopores of silica NTs, which are vertically aligned with the open surfaces of top-bottom ends inside the AAM. Third, we present the bench-top filtration method as a powerful tool for the size-exclusion separation of macromolecules. Significantly, the evaluation of the intrinsic properties of mesofilters (e.g., diffusivity, separation efficiency, long-term stability, and reusability) compared them with commercial, mature membranes used for separation of macromolecules.

    元の言語English
    ページ(範囲)447-458
    ページ数12
    ジャーナルTrAC - Trends in Analytical Chemistry
    30
    発行部数3
    DOI
    出版物ステータスPublished - 2011 3

      フィンガープリント

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Spectroscopy
    • Environmental Chemistry

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