Developing thermal endoscope for endoscopic photothermal therapy for peritoneal dissemination

Mutsuki Ohara, Sohta Sanpei, Chanjin Seo, Jun Ohya, Ken Masamune, Hiroshi Nagahashi, Yuji Morimoto, Manabu Harada

研究成果: Conference contribution

抄録

As a novel therapy for peritoneal dissemination, it is desired to actualize an endoscopic photothermal therapy, which is minimally invasive and is highly therapeutically effective. However, since the endoscopic tumor temperature control has not been actualized, conventional therapies could damage healthy tissues by overhearing. In this paper, we develop a thermal endoscope system that controls the tumor temperature so that the heated tumor gets necrotic. In fact, our thermal endoscope contains a thermal image sensor, a visible light endoscope and a laser fiber. Concerning the thermal image sensor, the conventional thermal endoscope has the problem that the diameter is too large, because the conventional endoscope loads a large thermal image sensor with high-resolution. Therefore, this paper uses a small thermal image sensor with low resolution, because the diameter of the thermal endoscope needs to be smaller than 15mm in order to be inserted into the trocar. However, this thermal image sensor is contaminated by much noise. Thus, we develop a tumor temperature control system using a feedback control and tumor temperature estimation based on Gaussian function, so that the noisy, small thermal image sensor can be used. As experimental results of the proposed endoscopic photothermal therapy for the hepatophyma carcinoma model of rats, it turns out that the tumor temperature by which the heated tumor gets necrotic can be kept stable. It can be said that our endoscopic photothermal therapy achieves a certain degree of therapy effect.

本文言語English
ホスト出版物のタイトル2020 IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2020
出版社Institute of Electrical and Electronics Engineers Inc.
ページ3040-3047
ページ数8
ISBN(電子版)9781728162126
DOI
出版ステータスPublished - 2020 10 24
イベント2020 IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2020 - Las Vegas, United States
継続期間: 2020 10 242021 1 24

出版物シリーズ

名前IEEE International Conference on Intelligent Robots and Systems
ISSN(印刷版)2153-0858
ISSN(電子版)2153-0866

Conference

Conference2020 IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2020
国/地域United States
CityLas Vegas
Period20/10/2421/1/24

ASJC Scopus subject areas

  • 制御およびシステム工学
  • ソフトウェア
  • コンピュータ ビジョンおよびパターン認識
  • コンピュータ サイエンスの応用

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