Any part of a live human body bears constant dynamic changes in the spatial and temporal axis. Therefore we believe that analyzing and understanding the 4 dimensional dynamics of a human body will contribute to new inputs in medical diagnosis and doctor’s judgment for effective treatment. To achieve this objective, we are developing a quantitative 4D human body model with inner structures such as the skeletal structure and major organs. We are aiming to grasp from various viewpoints, the spatiotemporal (four-dimensional) changes of an anatomical structure of a live human being. The model in this research is constructed based on a subject measured by MRI. The aim is to have the model’s inner structures change according to the subject’s full body movement data. In addition, we aim to have a function in which the shape of the skin surface changes synchronizing with the data. In this research, we examine the possibilities of clinical application of our 4D model that not only has skeletal and major organ blood vessel systems but also has muscular systems as inner structure.