抄録
Ultra-thin polymer films (nanosheets) fabricated by a layer-by-layer (LbL) method possess unique properties such as high flexibility, adhesive strength, and transparency, and can be peeled off from a substrate and attached to various surfaces via a water-soluble supporting film. Therefore, flexible and transferrable LbL nanosheets are convenient tools as coating materials. Here, we fabricated a novel antimicrobial coating material by embedding silver nanoparticles (AgNPs) in an LbL nanosheet composed of layers of chitosan and sodium alginate (Ag-LbL nanosheet) by means of a photo-reduction method. Optimizing the amount of irradiated energy applied led to robust antimicrobial efficacy against methicillin-resistant Staphylococcus aureus (MRSA), sufficient to meet ISO standards (ISO 22196), while maintaining the flexibility and adhesive potency of the LbL nanosheet. Thus, the Ag-LbL nanosheet is a promising coating material that can provide antimicrobial efficacy to various surfaces.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 585-593 |
| ページ数 | 9 |
| ジャーナル | Journal of Biomedical Materials Research - Part B Applied Biomaterials |
| 巻 | 104 |
| 号 | 3 |
| DOI | |
| 出版ステータス | Published - 2016 4 1 |
ASJC Scopus subject areas
- 生体材料
- 生体医工学