Development of an integrated system for rapid detection of biological agents

Hideyuki Terazono, Hiroyuki Takei, Masahito Hayashi, Akihiro Hattori, Kenji Yasuda

研究成果: Conference contribution

2 被引用数 (Scopus)

抄録

Weaponized biological agents are as great a threat as nuclear or chemical weapons. They must be detected at the earliest stage to prevent diffusion because once these agents are dispersed into the air, the rapidly decreasing concentration makes detection more of a challenge. Polymerase chain reaction (PCR) is a common method to create copies of a specific target region of a DNA sequence and to produce large quantities of DNA molecules. A few DNA molecules are rapidly amplified by PCR into billions of copies. While PCR is a powerful technique and is capable of countering new threats relatively easily, it is plagued by the number of processes necessary. Therefore, we have developed an integrated PCR system for rapid detection of biological agents captured from the air. Each processing function is performed by a dedicated module, and reduction in the process time has been made the top priority, without loss in the signal/noise ratio of the total system. Agents can be identified within 15 min from capture. A fully automated operation protects operators from exposure to potentially highly lethal samples.

本文言語English
ホスト出版物のタイトルChemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XI
DOI
出版ステータスPublished - 2010
外部発表はい
イベントChemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XI - Orlando, FL, United States
継続期間: 2010 4 62010 4 8

出版物シリーズ

名前Proceedings of SPIE - The International Society for Optical Engineering
7665
ISSN(印刷版)0277-786X

Other

OtherChemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XI
国/地域United States
CityOrlando, FL
Period10/4/610/4/8

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 凝縮系物理学
  • コンピュータ サイエンスの応用
  • 応用数学
  • 電子工学および電気工学

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