Development of DNA-conjugated microtubules for selective hybridization and transporting of target DNA

Shu Taira, Yong Zhong Du, Yuichi Hiratsuka, Kaoru Konishi, Tai Kubo, Taro Q.P. Uyeda, Noboru Yumoto, Masato Kodaka

研究成果: Paper査読

抄録

We have created a strategy in which hybridized-target DNA is not only detected but also transported using DNA-microtubules (MTs) conjugates and kinesin motor proteins. This technique is capable of collecting target biomolecules toward one point site. We have confirmed selective hybridization to target fully matched DNA and transport ability of DNA on the kinesin-coated substrate using the present DNA-conjugated MTs. By combining a technique to control the direction of MTs movement, this new system of selective detection and transport of DNA would be explored as a method for enrichment of DNA and DNA-affinity molecules.

本文言語English
ページ2326
ページ数1
出版ステータスPublished - 2005
外部発表はい
イベント54th SPSJ Annual Meeting 2005 - Yokohama, Japan
継続期間: 2005 5 252005 5 27

Conference

Conference54th SPSJ Annual Meeting 2005
国/地域Japan
CityYokohama
Period05/5/2505/5/27

ASJC Scopus subject areas

  • 工学(全般)

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