Development of prototype PET scanner using dual-sided readout DOI-PET modules

T. Fujita, Jun Kataoka, A. Kishimoto, Y. Kurei, T. Nishiyama, T. Ohshima, T. Taya

    研究成果: Article

    3 引用 (Scopus)

    抄録

    In our previous work, we proposed a novel design for a gamma-ray detector module capable of measuring the depth of interaction (DOI). In this paper, we further developed DOI-PET detector modules and a data acquisition system, and evaluated its performance. Each detector module was composed of a 3-D scintillator array and two large-area monolithic Multi-Pixel Photon Counter (MPPC) arrays coupled to both ends of the 3-D scintillator array, leading to only 8-ch signal outputs from a module. The 3-D scintillator array was composed of 9× 9 ×7 matrices of 1.0×1.0×3.0 mm3 Ce:GAGG crystals. The detector module showed good energy resolution of 10.6% as measured at 511 keV and a high average peak to valley ratio higher than 8 for each pixel crystal identified in the X-Y-Z directions. Moreover, we evaluated the spatial resolution of a virtual 18-ch PET gantry simulated by using two detector modules that were flexibly controlled using both the X-stage and θ-stage in 20-degree steps. By measuring a 22Na point source (0.25 mm in diameter), we showed that spatial resolution substantially degrades from 1.0 mm to 7.8 mm (FWHM; as measured at 0 mm and 28 mm off-center) with a non-DOI configuration, whereas the corresponding values for the DOI configuration were 0.9 mm and 1.5 mm, respectively (FWHM; as measured at 0 mm and 28 mm off-center). This preliminary study confirms that our DOI-PET module is useful for future high spatial resolution and compact small-animal PET scanners without radial image distortions at the peripheral regions of the field of view (FOV).

    元の言語English
    記事番号P12015
    ジャーナルJournal of Instrumentation
    9
    発行部数12
    DOI
    出版物ステータスPublished - 2014 12 17

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    Scanner
    scanners
    readout
    modules
    prototypes
    Prototype
    Detectors
    Module
    Phosphors
    Interaction
    Scintillator
    Detector
    Full width at half maximum
    detectors
    scintillation counters
    interactions
    spatial resolution
    Spatial Resolution
    Pixels
    3D

    ASJC Scopus subject areas

    • Instrumentation
    • Mathematical Physics

    これを引用

    Development of prototype PET scanner using dual-sided readout DOI-PET modules. / Fujita, T.; Kataoka, Jun; Kishimoto, A.; Kurei, Y.; Nishiyama, T.; Ohshima, T.; Taya, T.

    :: Journal of Instrumentation, 巻 9, 番号 12, P12015, 17.12.2014.

    研究成果: Article

    Fujita, T, Kataoka, J, Kishimoto, A, Kurei, Y, Nishiyama, T, Ohshima, T & Taya, T 2014, 'Development of prototype PET scanner using dual-sided readout DOI-PET modules', Journal of Instrumentation, 巻. 9, 番号 12, P12015. https://doi.org/10.1088/1748-0221/9/12/P12015
    Fujita, T. ; Kataoka, Jun ; Kishimoto, A. ; Kurei, Y. ; Nishiyama, T. ; Ohshima, T. ; Taya, T. / Development of prototype PET scanner using dual-sided readout DOI-PET modules. :: Journal of Instrumentation. 2014 ; 巻 9, 番号 12.
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    abstract = "In our previous work, we proposed a novel design for a gamma-ray detector module capable of measuring the depth of interaction (DOI). In this paper, we further developed DOI-PET detector modules and a data acquisition system, and evaluated its performance. Each detector module was composed of a 3-D scintillator array and two large-area monolithic Multi-Pixel Photon Counter (MPPC) arrays coupled to both ends of the 3-D scintillator array, leading to only 8-ch signal outputs from a module. The 3-D scintillator array was composed of 9× 9 ×7 matrices of 1.0×1.0×3.0 mm3 Ce:GAGG crystals. The detector module showed good energy resolution of 10.6{\%} as measured at 511 keV and a high average peak to valley ratio higher than 8 for each pixel crystal identified in the X-Y-Z directions. Moreover, we evaluated the spatial resolution of a virtual 18-ch PET gantry simulated by using two detector modules that were flexibly controlled using both the X-stage and θ-stage in 20-degree steps. By measuring a 22Na point source (0.25 mm in diameter), we showed that spatial resolution substantially degrades from 1.0 mm to 7.8 mm (FWHM; as measured at 0 mm and 28 mm off-center) with a non-DOI configuration, whereas the corresponding values for the DOI configuration were 0.9 mm and 1.5 mm, respectively (FWHM; as measured at 0 mm and 28 mm off-center). This preliminary study confirms that our DOI-PET module is useful for future high spatial resolution and compact small-animal PET scanners without radial image distortions at the peripheral regions of the field of view (FOV).",
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    AU - Fujita, T.

    AU - Kataoka, Jun

    AU - Kishimoto, A.

    AU - Kurei, Y.

    AU - Nishiyama, T.

    AU - Ohshima, T.

    AU - Taya, T.

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