TY - CHAP
T1 - Differences in muscle O2 dynamics during treadmill exercise between aerobic capacity-matched overweight and normal-weight adults
AU - Takagi, Shun
AU - Kime, Ryotaro
AU - Midorikawa, Taishi
AU - Niwayama, Masatsugu
AU - Sakamoto, Shizuo
AU - Katsumura, Toshihito
PY - 2020
Y1 - 2020
N2 - The aim of this study was to compare muscle O2 dynamics during exercise between aerobic capacity-matched overweight and normal-weight adults. Overweight women (OW, n = 9) and normal-weight women (NW, n = 14) performed graded treadmill exercise until exhaustion. Muscle O2 saturation (SmO2) and relative changes from rest in deoxygenated hemoglobin concentration (∆deoxy-Hb) and total hemoglobin concentration (∆total-Hb) were monitored continuously at gastrocnemius medialis muscle by near infrared spatial resolved spectroscopy. Significantly higher SmO2 and lower ∆deoxy-Hb and ∆total-Hb were observed in OW compared with NW. Pulmonary O2 uptake (VO2) normalized by fat-free mass was matched between groups. In both groups, peak VO2 was significantly correlated with change in SmO2 and ∆deoxy-Hb. Our findings suggest that both muscle blood volume and deoxygenation were lower in overweight adults, compared to aerobic capacity-matched normal-weight adults. Moreover, lowered muscle O2 extraction was related to peak VO2 in overweight adults, as well as in normal-weight adults.
AB - The aim of this study was to compare muscle O2 dynamics during exercise between aerobic capacity-matched overweight and normal-weight adults. Overweight women (OW, n = 9) and normal-weight women (NW, n = 14) performed graded treadmill exercise until exhaustion. Muscle O2 saturation (SmO2) and relative changes from rest in deoxygenated hemoglobin concentration (∆deoxy-Hb) and total hemoglobin concentration (∆total-Hb) were monitored continuously at gastrocnemius medialis muscle by near infrared spatial resolved spectroscopy. Significantly higher SmO2 and lower ∆deoxy-Hb and ∆total-Hb were observed in OW compared with NW. Pulmonary O2 uptake (VO2) normalized by fat-free mass was matched between groups. In both groups, peak VO2 was significantly correlated with change in SmO2 and ∆deoxy-Hb. Our findings suggest that both muscle blood volume and deoxygenation were lower in overweight adults, compared to aerobic capacity-matched normal-weight adults. Moreover, lowered muscle O2 extraction was related to peak VO2 in overweight adults, as well as in normal-weight adults.
KW - Blood volume
KW - Muscle O extraction
KW - Near infrared spectroscopy
KW - Regional difference
KW - Women
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U2 - 10.1007/978-3-030-34461-0_28
DO - 10.1007/978-3-030-34461-0_28
M3 - Chapter
C2 - 31893414
AN - SCOPUS:85077446373
T3 - Advances in Experimental Medicine and Biology
SP - 223
EP - 229
BT - Advances in Experimental Medicine and Biology
PB - Springer
ER -