Distribution of polymorphic gene duplication at the Gpdh locus in natural populations of Drosophila melanogaster

A. Koga, H. Baba, S. Kusakabe, Masahira Hattori, T. Mukai

研究成果: Article査読

1 被引用数 (Scopus)

抄録

The glycerol-3-phosphate dehydrogenase (GPDH, E.C. 1.1.1.8) gene of Drosophila melanogaster contains a tandem duplication of a 4.5-kb-long DNA fragment. Survey of the Gpdh gene region by the Southern blot analysis revealed the following features of this gene duplication: (1) The duplication was not observed in chromosome lines that carry In(2L)t, a cosmopolitan chromosomal inversion in this species. The duplication and the inversion are in linkage disequilibrium. (2) The duplication is polymorphic in the Japan and US natural populations examined. Its frequency is 0.26 on an average in In(2L)t-free chromosomes. (3) Triplication is absent or has not become frequent in the populations surveyed. Possible evolutionary factors of this duplication polymorphism are discussed.

本文言語English
ページ(範囲)532-535
ページ数4
ジャーナルJournal of Molecular Evolution
36
6
DOI
出版ステータスPublished - 1993
外部発表はい

ASJC Scopus subject areas

  • 遺伝学
  • 生化学
  • 生化学、遺伝学、分子生物学(全般)
  • 遺伝学(臨床)
  • 生態、進化、行動および分類学
  • 分子生物学
  • 農業および生物科学(全般)
  • 農業および生物科学(その他)

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