抄録
S-Acetamidomethyl (Acm) cysteine was found to be converted quantitatively to cystine by deprotection of the Acm group with silver trifluoromethanesulfonate (AgOTf) followed by dimethylsulfoxide (DMSO) / aqueous hydrochloric acid (HCl) treatment. No significant side reactions were observed with oxidation-sensitive amino acids such as Met, Tyr, and Trp under these reaction conditions. This method has been applied successfully to the syntheses of oxytocin and a Trp-containing peptide, urotensin II.
本文言語 | English |
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ページ(範囲) | 4931-4934 |
ページ数 | 4 |
ジャーナル | Tetrahedron Letters |
巻 | 34 |
号 | 31 |
DOI | |
出版ステータス | Published - 1993 7月 30 |
外部発表 | はい |
ASJC Scopus subject areas
- 生化学
- 創薬
- 有機化学