Diurnal changes in the synthesis of the neurosteroid 7α- hydroxypregnenolone stimulating locomotor activity in newts

Teppei Koyama, Shogo Haraguchi, Hubert Vaudry, Kazuyoshi Tsutsui

    研究成果: Conference contribution

    9 引用 (Scopus)

    抜粋

    We recently identified 7α-hydroxypregnenolone as a novel amphibian neurosteroid stimulating locomotor activity in newts. Because male newts show marked diurnal changes in locomotor activity, we hypothesized that 7α-hydroxypregnenolone may be a key factor for the induction of diurnal changes in locomotor activity in male newts. In this study, we found diurnal changes in 7α-hydroxypregnenolone synthesis in the brain of male newts, which paralleled locomotor activity. Interestingly, the production of 7α-hydroxypregnenolone in the male newt brain increased during the dark phase when locomotor activity of males was high.

    元の言語English
    ホスト出版物のタイトルAnnals of the New York Academy of Sciences
    ページ444-447
    ページ数4
    1163
    DOI
    出版物ステータスPublished - 2009 4

    出版物シリーズ

    名前Annals of the New York Academy of Sciences
    1163
    ISSN(印刷物)00778923
    ISSN(電子版)17496632

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

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  • これを引用

    Koyama, T., Haraguchi, S., Vaudry, H., & Tsutsui, K. (2009). Diurnal changes in the synthesis of the neurosteroid 7α- hydroxypregnenolone stimulating locomotor activity in newts. : Annals of the New York Academy of Sciences (巻 1163, pp. 444-447). (Annals of the New York Academy of Sciences; 巻数 1163). https://doi.org/10.1111/j.1749-6632.2008.03622.x