Diurnal changes in the synthesis of the neurosteroid 7α- hydroxypregnenolone stimulating locomotor activity in newts

Teppei Koyama, Shogo Haraguchi, Hubert Vaudry, Kazuyoshi Tsutsui*

*この研究の対応する著者

    研究成果: Conference contribution

    9 被引用数 (Scopus)

    抄録

    We recently identified 7α-hydroxypregnenolone as a novel amphibian neurosteroid stimulating locomotor activity in newts. Because male newts show marked diurnal changes in locomotor activity, we hypothesized that 7α-hydroxypregnenolone may be a key factor for the induction of diurnal changes in locomotor activity in male newts. In this study, we found diurnal changes in 7α-hydroxypregnenolone synthesis in the brain of male newts, which paralleled locomotor activity. Interestingly, the production of 7α-hydroxypregnenolone in the male newt brain increased during the dark phase when locomotor activity of males was high.

    本文言語English
    ホスト出版物のタイトルAnnals of the New York Academy of Sciences
    ページ444-447
    ページ数4
    1163
    DOI
    出版ステータスPublished - 2009 4月

    出版物シリーズ

    名前Annals of the New York Academy of Sciences
    1163
    ISSN(印刷版)00778923
    ISSN(電子版)17496632

    ASJC Scopus subject areas

    • 生化学、遺伝学、分子生物学(全般)

    フィンガープリント

    「Diurnal changes in the synthesis of the neurosteroid 7α- hydroxypregnenolone stimulating locomotor activity in newts」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

    引用スタイル