Droplet network connected by biological nanopores for DNA computing

Hiroki Yasuga, R. Kawano, M. Takinoue, Y. Tsuji, T. Osaki, K. Kamiya, N. Miki, S. Takeuchi

研究成果: Conference contribution

6 引用 (Scopus)

抜粋

This paper experimentally describes formation of lipid-coated droplet network and demonstrates a biological NAND logic gate using this network and DNA. Droplets which compose this network are comparted by bilayer lipid membranes (BLMs) and connected via biological nanopores of membrane proteins, which ssDNA passes through. In the geometry of the droplet network, four droplets were placed at the corners and the center of an equilateral triangle. Inputs corresponded to the DNA translocation via biological nanopores from the two droplets at the corners (#1 and 2 in Fig. 1) to the center (#3 in Fig. 1), which can be controlled by the applied electrical fields between the droplets. Output was determined by whether DNA translocation occurred through nanopores between the center (#3 in Fig. 1) and the other corner droplet (#4 in Fig. 1). We believe that this system enables direct connection between electrical systems and computing with biomolecules.

元の言語English
ホスト出版物のタイトル2013 Transducers and Eurosensors XXVII
ホスト出版物のサブタイトルThe 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
ページ1221-1222
ページ数2
DOI
出版物ステータスPublished - 2013 12 1
外部発表Yes
イベント2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 - Barcelona, Spain
継続期間: 2013 6 162013 6 20

出版物シリーズ

名前2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

Conference

Conference2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Spain
Barcelona
期間13/6/1613/6/20

ASJC Scopus subject areas

  • Hardware and Architecture
  • Electrical and Electronic Engineering

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  • これを引用

    Yasuga, H., Kawano, R., Takinoue, M., Tsuji, Y., Osaki, T., Kamiya, K., Miki, N., & Takeuchi, S. (2013). Droplet network connected by biological nanopores for DNA computing. : 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 (pp. 1221-1222). [6626994] (2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013). https://doi.org/10.1109/Transducers.2013.6626994