Dynamic control of cell adhesion on a stiffness-tunable substrate for analyzing the mechanobiology of collective cell migration

Masao Kamimura, Michiko Sugawara, Shota Yamamoto, Kazuo Yamaguchi, Jun Nakanishi

研究成果: Article査読

21 被引用数 (Scopus)

抄録

A method was developed for photocontrolling cell adhesion on a gel substrate with defined mechanical properties. Precise patterning of geometrically controlled cell clusters and their migration induction became possible by spatiotemporally controlled photo-irradiation of the substrate. The clusters exhibited unique collective motion that depended on substrate stiffness and cluster geometry.

本文言語English
ページ(範囲)933-937
ページ数5
ジャーナルBiomaterials Science
4
6
DOI
出版ステータスPublished - 2016 6
外部発表はい

ASJC Scopus subject areas

  • Biomedical Engineering
  • Materials Science(all)

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