Effect of activin A and follistatin on the release of pituitary hormones in the bullfrog Rana catesbeiana

Aya Koda, Kazutoshi Yamamoto, Hideho Uchiyama, Hubert Vaudry, Sakae Kikuyama*

*この研究の対応する著者

    研究成果: Article査読

    8 被引用数 (Scopus)

    抄録

    The effects of activin A and follistatin on the release of follicle-stimulating hormone (FSH), luteinizing hormone (LH), growth hormone (GH) and prolactin (PRL) from dispersed pituitary cells of the bullfrogs Rana catesbeiana were studied. Activin A stimulated the release of FSH, GH, and PRL dose-dependently, but not that of LH. Follistatin suppressed the activin-induced FSH, GH, and PRL release, but did not affect the basal secretion of those hormones. From the results obtained in this experiment, together with the previously obtained findings that activin B enhanced the release of FSH, LH, GH, and PRL, we conclude that activin A, in addition to activin B, influences the function of multiple types of pituitary cells in the bullfrog.

    本文言語English
    ページ(範囲)971-975
    ページ数5
    ジャーナルZoological Science
    17
    7
    出版ステータスPublished - 2000 9

    ASJC Scopus subject areas

    • 動物科学および動物学

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