Effect of bifurcation on pulse wave propagation in human arteries

Yusuke Kawai, Shigehiko Kaneko

研究成果: Conference contribution

抜粋

In recent years, arteriosclerotic cardiovascular disease becomes a serious problem in the developed countries. The degree of the arteriosclerosis should be examined routinely and invasively, and the measurement of pulse wave is considered as an effective estimation method. Nowadays, pulse wave is widely used in clinical practice as a noninvasive method of examining circulatory kinetics, but the mechanism in the process of the systolic wave generated at heart and propagating to the peripheral artery remains to be elucidated. In this research, to investigate the effect of bifurcation on pulse wave propagation, numerical simulations by a dynamic model of arteries and in vitro experiments were conducted. A onedimensional model of arteries is coupled by partial differential equations describing mass and momentum conservation with the tube law that relates the local cross-sectional area to the local radial pressure difference. In the case of a bifurcated artery model, the governing equations were solved by introducing the momentum caused by the reactive force at bifurcation into the equation of momentum conservation. The momentum by the reactive force at bifurcation was supposed to be proportional to the momentum flowing into the bifurcation, and the proportionality coefficient was derived from experiments. Then, the proposed one-dimensional model was validated by a comparison to experimental data. In the experimental setup, elastic tubes with different values of Young's modulus were tested to simulate human arteries. From the numerical and experimental results, it turns out that the characteristic waveforms of the pressure and velocity obtained from experiments are also captured by the numerical calculations.

元の言語English
ホスト出版物のタイトルASME 2010 3rd Joint US-European Fluids Engineering Summer Meeting Collocated with 8th International Conference on Nanochannels, Microchannels, and Minichannels, FEDSM2010
ページ983-989
ページ数7
エディションPARTS A AND B
DOI
出版物ステータスPublished - 2010 12 1
イベントASME 2010 3rd Joint US-European Fluids Engineering Summer Meeting, FEDSM 2010 - ASME 2010 7th International Symposium on Fluid-Structure Interactions, Flow-Sound Interactions, and Flow-Induced Vibration and Noise, FSI2 and FIV+N - Montreal, QC, Canada
継続期間: 2010 8 12010 8 5

出版物シリーズ

名前American Society of Mechanical Engineers, Fluids Engineering Division (Publication) FEDSM
番号PARTS A AND B
3
ISSN(印刷物)0888-8116

Conference

ConferenceASME 2010 3rd Joint US-European Fluids Engineering Summer Meeting, FEDSM 2010 - ASME 2010 7th International Symposium on Fluid-Structure Interactions, Flow-Sound Interactions, and Flow-Induced Vibration and Noise, FSI2 and FIV+N
Canada
Montreal, QC
期間10/8/110/8/5

    フィンガープリント

ASJC Scopus subject areas

  • Mechanical Engineering

これを引用

Kawai, Y., & Kaneko, S. (2010). Effect of bifurcation on pulse wave propagation in human arteries. : ASME 2010 3rd Joint US-European Fluids Engineering Summer Meeting Collocated with 8th International Conference on Nanochannels, Microchannels, and Minichannels, FEDSM2010 (PARTS A AND B 版, pp. 983-989). (American Society of Mechanical Engineers, Fluids Engineering Division (Publication) FEDSM; 巻数 3, 番号 PARTS A AND B). https://doi.org/10.1115/FEDSM-ICNMM2010-30675