Effect of electrochemically structured titanium alloys on cell morphology

S. Roy*, Qi Bai Wu, S. Nouraei, S. Ngalim, M. Birch, A. McCaskie, H. Zhang, T. Osaka

*この研究の対応する著者

研究成果: Conference contribution

抄録

Ti alloys are commonly used as dental and orthopaedic implants. It has been shown that surface topography can influence cell genesis, behaviour and growth. In this work we have electropolished and micro-patterned Ti-6Al-4V alloy to study the effect of surface topography on cell morphology. Electroetching was carried out in a flat cell under galvanostatic polarisation of 5.0 V and 9.0 V vs. SCE, using a 3.0 M H2SO4 - methanol electrolyte. Electropolishing conditions were achieved when the overpotential was 9.0 V. Micropatterning of Ti alloy substrates was carried out at the same potentials by etching through mask; a methanol stable SU-8 photoresist was used for this purpose. Human mesenchymal stem cells were seeded and grown on these substrates. It was found that surface nano and micro scale topography influenced cell numbers and morphology, respectively.

本文言語English
ホスト出版物のタイトルECS Transactions - Biological Nanostructures, Materials, and Applications - 214th ECS Meeting
ページ17-25
ページ数9
38
DOI
出版ステータスPublished - 2009 11 23
イベントBiological Nanostructures, Materials, and Applications - 214th ECS Meeting - Honolulu, HI, United States
継続期間: 2008 10 122008 10 17

出版物シリーズ

名前ECS Transactions
番号38
16
ISSN(印刷版)1938-5862
ISSN(電子版)1938-6737

Conference

ConferenceBiological Nanostructures, Materials, and Applications - 214th ECS Meeting
国/地域United States
CityHonolulu, HI
Period08/10/1208/10/17

ASJC Scopus subject areas

  • 工学(全般)

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