Effects of alcohol on thermoregulation during mild heat exposure in humans

Tamae Yoda*, Larry I. Crawshaw, Mayumi Nakamura, Kumiko Saito, Aki Konishi, Kei Nagashima, Sunao Uchida, Kazuyuki Kanosue


研究成果: Article査読

28 被引用数 (Scopus)


We investigated the effects of alcohol on thermoregulatory responses and thermal sensations during mild heat exposure in humans. Eight healthy men participated in this study. Experiments were conducted twice for each subject at a room temperature of 33°C. After a 30-min resting period, the subject drank either 15% alcohol (alcohol session) at a dose of 0.36 g/kg body weight or equal volume of water (control session). Skin blood flow and chest sweat rate in the alcohol session significantly increased over those in controls 10 min after drinking. Deep body temperature in the alcohol session started to decrease 20 min after the onset of sweating and eventually fell 0.3°C lower than in the controls. Whole body hot sensation transiently increased after alcohol drinking, whereas it changed little after water drinking. The increased "hot" sensation would presumably cause cool-seeking behavior, if permitted. Thus, alcohol influences thermoregulation so that body core temperature is lowered not only by automatic mechanisms (sweating and skin vasodilation) but also behaviorally. These results suggest that decreases in body temperature after alcohol drinking are not secondary to skin vasodilation, a well-known effect of alcohol, but rather result from a decrease in the regulated body temperature evidenced by the coordinated modulation of various effectors of thermoregulation and sensation.

出版ステータスPublished - 2005 7月

ASJC Scopus subject areas

  • 健康(社会科学)
  • 生化学
  • 毒物学
  • 神経学
  • 行動神経科学


「Effects of alcohol on thermoregulation during mild heat exposure in humans」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。