Effects of an upstream DNA curvature on the strength of HSV thymidine kinase promoter.

T. Ohyama, Y. Kadokawa, Y. Hirota

研究成果: Article査読

抄録

The effect of an upstream DNA curvature on the strength of the herpes simplex virus thymidine kinase (TK) promoter was investigated by employing luciferase assay. A set of double-stranded oligonucleotides, each with an unique DNA configuration, were synthesized and substituted into an upstream region of the promoter. It was revealed from the assay that both plane and space curves exerted a negative influence upon the strength of the promoter.

本文言語English
ページ(範囲)67-68
ページ数2
ジャーナルNucleic acids symposium series
34
出版ステータスPublished - 1995
外部発表はい

ASJC Scopus subject areas

  • Medicine(all)

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