抄録
The purpose of this study was to investigate the effects of curcumin supplementation on exercise-induced oxidative stress in humans. 10 male participants, ages 26.8±2.0 years (mean±SE), completed 3 trials in a random order: (1) placebo (control), (2) single (only before exercise) and (3) double (before and immediately after exercise) curcumin supplementation trials. Each participant received oral administration of 90 mg of curcumin or the placebo 2h before exercise and immediately after exercise. Each participant walked or ran at 65% of V̇2max on a treadmill for 60min. Blood samples were collected pre-exercise, immediately after exercise and 2h after exercise. The concentrations of serum derivatives of reactive oxygen metabolites measured immediately after exercise were significantly higher than pre-exercise values in the placebo trial (308.8±12.9 U. CARR, P<0.05), but not in the single (259.9±17.1 U. CARR) or double (273.6±19.7 U. CARR) curcumin supplementation trials. Serum biological antioxidant potential concentrations measured immediately after exercise were significantly elevated in the single and double curcumin supplementation trials compared with pre-exercise values (P<0.05). These findings indicate that curcumin supplementation can attenuate exercise-induced oxidative stress by increasing blood antioxidant capacity.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 469-475 |
| ページ数 | 7 |
| ジャーナル | International Journal of Sports Medicine |
| 巻 | 35 |
| 発行部数 | 6 |
| DOI | |
| 出版物ステータス | Published - 2014 |
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ASJC Scopus subject areas
- Orthopedics and Sports Medicine
- Medicine(all)
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Effects of curcumin supplementation on exercise-induced oxidative stress in humans. / Takahashi, Masaki; Suzuki, Katsuhiko; Kim, Hyeonki; Otsuka, Y.; Imaizumi, A.; Miyashita, Masashi; Sakamoto, Shizuo.
：: International Journal of Sports Medicine, 巻 35, 番号 6, 2014, p. 469-475.研究成果: Article
}
TY - JOUR
T1 - Effects of curcumin supplementation on exercise-induced oxidative stress in humans
AU - Takahashi, Masaki
AU - Suzuki, Katsuhiko
AU - Kim, Hyeonki
AU - Otsuka, Y.
AU - Imaizumi, A.
AU - Miyashita, Masashi
AU - Sakamoto, Shizuo
PY - 2014
Y1 - 2014
N2 - The purpose of this study was to investigate the effects of curcumin supplementation on exercise-induced oxidative stress in humans. 10 male participants, ages 26.8±2.0 years (mean±SE), completed 3 trials in a random order: (1) placebo (control), (2) single (only before exercise) and (3) double (before and immediately after exercise) curcumin supplementation trials. Each participant received oral administration of 90 mg of curcumin or the placebo 2h before exercise and immediately after exercise. Each participant walked or ran at 65% of V̇2max on a treadmill for 60min. Blood samples were collected pre-exercise, immediately after exercise and 2h after exercise. The concentrations of serum derivatives of reactive oxygen metabolites measured immediately after exercise were significantly higher than pre-exercise values in the placebo trial (308.8±12.9 U. CARR, P<0.05), but not in the single (259.9±17.1 U. CARR) or double (273.6±19.7 U. CARR) curcumin supplementation trials. Serum biological antioxidant potential concentrations measured immediately after exercise were significantly elevated in the single and double curcumin supplementation trials compared with pre-exercise values (P<0.05). These findings indicate that curcumin supplementation can attenuate exercise-induced oxidative stress by increasing blood antioxidant capacity.
AB - The purpose of this study was to investigate the effects of curcumin supplementation on exercise-induced oxidative stress in humans. 10 male participants, ages 26.8±2.0 years (mean±SE), completed 3 trials in a random order: (1) placebo (control), (2) single (only before exercise) and (3) double (before and immediately after exercise) curcumin supplementation trials. Each participant received oral administration of 90 mg of curcumin or the placebo 2h before exercise and immediately after exercise. Each participant walked or ran at 65% of V̇2max on a treadmill for 60min. Blood samples were collected pre-exercise, immediately after exercise and 2h after exercise. The concentrations of serum derivatives of reactive oxygen metabolites measured immediately after exercise were significantly higher than pre-exercise values in the placebo trial (308.8±12.9 U. CARR, P<0.05), but not in the single (259.9±17.1 U. CARR) or double (273.6±19.7 U. CARR) curcumin supplementation trials. Serum biological antioxidant potential concentrations measured immediately after exercise were significantly elevated in the single and double curcumin supplementation trials compared with pre-exercise values (P<0.05). These findings indicate that curcumin supplementation can attenuate exercise-induced oxidative stress by increasing blood antioxidant capacity.
KW - antioxidant capacity
KW - curcumin
KW - endurance exercise
KW - oxidative stress
UR - http://www.scopus.com/inward/record.url?scp=84901610866&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901610866&partnerID=8YFLogxK
U2 - 10.1055/s-0033-1357185
DO - 10.1055/s-0033-1357185
M3 - Article
C2 - 24165958
AN - SCOPUS:84901610866
VL - 35
SP - 469
EP - 475
JO - International Journal of Sports Medicine
JF - International Journal of Sports Medicine
SN - 0172-4622
IS - 6
ER -