The influence of age and gender on salivary secretory immunoglobulin A (SIgA) in response to moderate exercise training was studied in 158 elderly subjects. Subjects were assigned to an exercise training group (EXC: 51 males, 74 females) or a non-exercise control group (CON: 11 males, 22 females). The subjects in each group were separated into four age-gender subgroups (60-69-yr-old males, over 70-yr-old males, 60-69-yr-old females, over 70-yr-old females) and compared by age and gender. Subjects in EXC participated in exercise sessions 5-days a week for 6 months. Saliva samples were collected both before and after the study period. The SIgA secretion rates were significantly increased after training (p < 0.05) in all the age-gender subgroups of EXC (60-69 males: 41%, over 70 males: 55%, 60-69 females: 40%, over 70 females: 38%); no age- or gender-related differences were observed. On the other hand, none of the age-gender sub-groups of CON showed significant changes in the SIgA secretion rate; also, there were no age- or gender-related differences. In conclusion, enhancement of mucosal immune function following regular moderate exercise training occurs in elderlies in their 60s and over 70 years, and in both, males and females.
|ジャーナル||Exercise immunology review|
|出版ステータス||Published - 2007 12 1|
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