@article{d78d96d5ee9444199b7c5170d6c810b2,
title = "Effects of implantation on the mechanical properties of the Polyurethane diaphragm of left ventricular assist devices",
abstract = "Tensile properties of blood pump diaphragms made from a segmented polyether polyurethane (Toyobo TM5) were studied after implanting in goats for variable periods of time up to 72 days. The implantation decreased the tensile strength and ultimate elongation at break, while the elastic modulus increased very slightly. These changes in the strength and ductility were primarily caused by the contact of material with blood rather than by the mechanical fatigue of material. Mechanical stability was greatly improved by removing residual oligomers from the material by a refining procedure. The refined polyurethane has characteristics favourable for blood pump applications.",
keywords = "Polymers, Segmented polyether polyurethane, implantation, in vitro fatigue test, left ventricular assist device, tensile properties",
author = "Kozaburo Hayashi and Takehisa Matsuda and Hisateru Takano and Mitsuo Umezu and Yoshiyuki Taenaka and Takao Nakamura",
note = "Funding Information: This research work was supported financially in part by: Grant-in-Aid for Scientific Research from the Ministry of Education (No. 557322 and No. 57570520); Research Grant for Cardiovascular Diseases and Grant for Scientific Research Expenses for Health and Welfare Program from the Ministry of Health and Welfare; and Japan Heart Foundation Research Grant for 1981 (ali with Dr Kozaburo Hayashi as the principal investigator). The authors wish to thank Messrs K. Murayama and M. Tanaka of Toyobo Co. and DrT. Tsunetsugu of Sumitomo Bakelite Co. for providing materials used in this study.",
year = "1985",
month = mar,
doi = "10.1016/0142-9612(85)90068-7",
language = "English",
volume = "6",
pages = "82--88",
journal = "Biomaterials",
issn = "0142-9612",
publisher = "Elsevier BV",
number = "2",
}