Electrical detection of biomolecules in a PDMS micro-fluidic channel using a MOSFET-type biosensor

Jang Kyoo Shin*, Dong Sun Kim, Geunbae Lim, Shuichi Shoji

*この研究の対応する著者

研究成果: Conference contribution

2 被引用数 (Scopus)

抄録

In this article, we report a MOSFET-type biosensor assembled in a polydimethylsiloxane (PDMS) micro-fluidic channel for the electrical detection of nano-scale biomolecules. The MOSFET-type sensor was fabricated on the basis of standard complementary metal oxide semiconductor (CMOS) technology. Au which has a chemical affinity with thiol by forming a self-assembled monolayer (SAM) was used as the gate metal. In order to apply to the hybrid micro-flow-system for a prototype lab-on-a-chip, the PDMS layer with the micro-channel was aligned along with the sensing area of the MOSFET device. Thiol which was injected into the micro-fluidic channel was detected by measuring the electrical characteristics of the MOSFET sensor in both ex-situ and in-situ due to the negative charge of thiol.

本文言語English
ホスト出版物のタイトルBiomedical Applications of Micro- and Nanoengineering III
DOI
出版ステータスPublished - 2007 4月 30
イベントBiomedical Applications of Micro- and Nanoengineering III - Adelaide, Australia
継続期間: 2006 12月 112006 12月 13

出版物シリーズ

名前Proceedings of SPIE - The International Society for Optical Engineering
6416
ISSN(印刷版)0277-786X

Conference

ConferenceBiomedical Applications of Micro- and Nanoengineering III
国/地域Australia
CityAdelaide
Period06/12/1106/12/13

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 凝縮系物理学
  • コンピュータ サイエンスの応用
  • 応用数学
  • 電子工学および電気工学

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