Electrophysiological studies of the development of suprachiasmatic neuronal activity in hypothalamic slice preparations

Shigenobu Shibata*, Yutaka Oomura, Shyh Yuh Liou, Showa Ueki

*この研究の対応する著者

研究成果: Article査読

21 被引用数 (Scopus)

抄録

The rate and pattern of neuronal discharge in the suprachiasmatic nucleus (SCN) during developmental stages were studied and compared with those of the ventromedial (VMH) and the lateral hypothalamus (LHA) using rat hypothalamic slices. The firing rate of the SCN neurons was low on the 7th and 11th days; however, it dramatically increased by the 14th day to reach the adult rate, while firing rates of VMH and LHA neurons increased gradually with age. The discharge rate of neurons in the ventrolateral part of the SCN (VL-SCN) was higher than that of the dorsomedial SCN (DM-SCN) neurons in 14-, 21- and 70-100-day-old rats. Activity of the DM-SCN neurons on day 21 were unaffected by bilateral enucleation on the third day, while activity in the VL-SCN decreased; that of both parts was significantly decreased by a constant light schedule.

本文言語English
ページ(範囲)29-35
ページ数7
ジャーナルDevelopmental Brain Research
13
1
DOI
出版ステータスPublished - 1984 3
外部発表はい

ASJC Scopus subject areas

  • 発達神経科学
  • 発生生物学

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