@article{c1ae5e9a7a5847298fff6af3e2b0403f,
title = "Enantioselective synthesis of chiral 5-carbamoyl-3-pyridyl alcohols by asymmetric autocatalytic reaction",
abstract = "A catalytic amount of a chiral zinc alkoxide of 5-carbamoyl-3-pyridyl alkyl alcohol catalyzes an enantioselective alkylation of 5-carbitmoylpyridine-3-carbaldehyde by diisopropylzinc to afford itself in up to 86% e.e. with the same configuration as the catalyst. Enantioselectivity is dependent on the structure of substituents on the nitrogen atom of the amide.",
author = "Takanori Shibata and Hiroshi Morioka and Shigehisa Tanji and Tadakatsu Hayase and Yasutaka Kodaka and Kenso Soai",
note = "Funding Information: Financial support by the New Energy and Industrial Technology Development Organization (NEDO) and by a Grant-in-Aid for Scientific Research from the Ministry and Education, Science, Sports and Culture is gratefully acknowledged.",
year = "1996",
month = nov,
day = "25",
doi = "10.1016/S0040-4039(96)02031-X",
language = "English",
volume = "37",
pages = "8783--8786",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "48",
}