Enantioselective total synthesis of convolutamydines B and E

Tomoaki Nakamura, Shin Ichi Shirokawa, Seijiro Hosokawa, Atsuo Nakazaki, Susumu Kobayashi

研究成果: Article

100 引用 (Scopus)

抜粋

The first enantioselective total synthesis of convolutamydines B and E has been achieved using our vinylogous Mukaiyama aldol reaction. The synthesis features highly diastereoselective vinylogous Mukaiyama aldol reaction with isatin instead of aldehydes to construct a chiral center of convolutamydines. Additionally, the absolute configuration of natural convolutamydine B has been determined as R by its CD spectrum.

元の言語English
ページ(範囲)677-679
ページ数3
ジャーナルOrganic Letters
8
発行部数4
DOI
出版物ステータスPublished - 2006 2 16

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

フィンガープリント Enantioselective total synthesis of convolutamydines B and E' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Nakamura, T., Shirokawa, S. I., Hosokawa, S., Nakazaki, A., & Kobayashi, S. (2006). Enantioselective total synthesis of convolutamydines B and E. Organic Letters, 8(4), 677-679. https://doi.org/10.1021/ol052871p