Encoding and decoding time in neural development

Kenichi Toma, Tien Cheng Wang, Carina Hanashima

研究成果: Review article査読

13 被引用数 (Scopus)

抄録

The development of a multicellular organism involves time-dependent changes in molecular and cellular states; therefore 'time' is an indispensable mathematical parameter of ontogenesis. Regardless of their inextricable relationship, there is a limited number of events for which the output of developmental phenomena primarily uses temporal cues that are generated through multilevel interactions between molecules, cells, and tissues. In this review, we focus on neural stem cells, which serve as a faithful decoder of temporal cues to transmit biological information and generate specific output in the developing nervous system. We further explore the identity of the temporal information that is encoded in neural development, and how this information is decoded into various cellular fate decisions. This review focus on neural stem cells as a decoder of temporal cues to transmit biological information and generate particular output in the developing nervous system.

本文言語English
ページ(範囲)59-72
ページ数14
ジャーナルDevelopment Growth and Differentiation
58
1
DOI
出版ステータスPublished - 2016 1 1
外部発表はい

ASJC Scopus subject areas

  • 発生生物学
  • 細胞生物学

フィンガープリント

「Encoding and decoding time in neural development」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル