Enzyme inhibitors from marine invertebrates

Youichi Nakao, Nobuhiro Fusetani

    研究成果: Chapter

    抄録

    Marine invertebrates are the rich source of small molecules with unique chemical skeletons and potent bioactivities; however, the major biological activities tested for marine natural products have been mainly limited to the traditional phenotype-oriented bioactivities such as cytotoxicity or antimicrobial activities. Enzyme inhibition is the target-oriented bioactivity and small molecule inhibitors are quite useful for controlling biological processes and understanding complicated biological phenomena. Recently, it has been recognized that the natural products are superior source of small molecule probes useful for the chemical biology. Especially, marine-derived enzyme inhibitors still remain to be fully investigated in spite of their high potentials as a source of unique compounds. In this chapter, selected enzyme inhibitors from marine invertebrates are described.

    本文言語English
    ホスト出版物のタイトルHandbook of Marine Natural Products
    出版社Springer Netherlands
    ページ1145-1229
    ページ数85
    ISBN(電子版)9789048138340
    ISBN(印刷版)9789048138333
    DOI
    出版ステータスPublished - 2012 1 1

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

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