Fabrication of a highly selective nonenzymatic amperometric sensor for hydrogen peroxide based on nickel foam/cytochrome c modified electrode

Naeem Akhtar, Sherif A. El-Safty*, Md Khairy, Waleed A. El-Said

*この研究の対応する著者

    研究成果査読

    51 被引用数 (Scopus)

    抄録

    The development of an accurate, rapid, and low-cost monitoring technique for hydrogen peroxide (H2O2) is an important issue in biology, medicine, and food industry to assess human health risks. Several electrochemical sensors for H2O2 detection have been reported. Although these sensors have demonstrated low detection limits with good stability and selectivity, most of them have complicated preparation processes. Therefore, a simple design is needed for controlled development of electrochemical sensor for detecting H2O2 in real samples with high flexibility and low capital cost. In this study, a simple H2O2 sensor was developed based on 3D porous nickel foam (Ni foam) electrode functionalized with cytochrome c (Cyt.c) as an electron transfer-mediating layer between active centers of the Ni foam (i.e., nickel hydroxide) and H2O2. Our findings revealed that the combination between Ni foam and Cyt.c could enhance the sensor performance in terms of sensitivity and selectivity, and allow the detection of H2O2 over a wide linear range with a detection limit of 2 × 10-7 M and a sensitivity of 1.95 μA mM-1. The Cyt.c/Ni foam sensor did not have potentially interfering components, such as ascorbic acid, uric acid, and dopamine; hence, is applicable for analyzing environmental samples, such as apple juice. This Cyt.c/Ni foam electrode enabled H2O2 sensing system responses with revisable, selective, and sensitive recognition of a wide range of H2O2 concentrations.

    本文言語English
    ページ(範囲)158-166
    ページ数9
    ジャーナルSensors and Actuators, B: Chemical
    207
    PA
    DOI
    出版ステータスPublished - 2015

    ASJC Scopus subject areas

    • 電子工学および電気工学
    • 凝縮系物理学
    • 電子材料、光学材料、および磁性材料
    • 金属および合金
    • 表面、皮膜および薄膜
    • 材料化学
    • 器械工学

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