Fabrication, Properties, and Biomedical Applications of Nanosheets

Toshinori Fujie, Yosuke Okamura, Shinji Takeoka

研究成果: Chapter

10 引用 (Scopus)

抜粋

Nanosheets, ultrathin sheet-shaped materials, have several advantages in the biomedical field; a large contact area in the biointerface, noncovalent adhesion, small amount ofmaterial required, and dual surfaces for heterofunctionalization. In terms of a drug-delivery vehicle, the sheet-shaped carriers perform unique dynamic functions over spherically shaped carriers. For surgical dressing, the sheet-shaped materials can densely overlap the tissue defect site without the need for chemical adhesive reagents. In this review, we propose a methodology for the preparation of freestanding, ultrathin nanosheets with a huge aspect ratio and heterosurfaces, fabricated through molecular assembly. In their practical biomedical applications, the micrometer-sized nanosheet was constructed by exploiting a micropatterned substrate with a precisely controlled size, applicable for injectable sheet-shaped drug carriers, whereas the giant nanosheets, with an aspect ratio of >106, can act as novel biomaterials for surgical dressing in the next generation of minimally invasive treatments.

元の言語English
ホスト出版物のタイトルFunctional Polymer Films
出版者Wiley-VCH
ページ907-931
ページ数25
2
ISBN(印刷物)9783527321902
DOI
出版物ステータスPublished - 2011 6 7

    フィンガープリント

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Materials Science(all)

これを引用

Fujie, T., Okamura, Y., & Takeoka, S. (2011). Fabrication, Properties, and Biomedical Applications of Nanosheets. : Functional Polymer Films (巻 2, pp. 907-931). Wiley-VCH. https://doi.org/10.1002/9783527638482.ch29