Facilitatory effect of olfactory bulbectomy on 2-deoxyglucose uptake in rat amygdala slices

Shigenobu Shibata*, Shigenori Watanabe

*この研究の対応する著者

研究成果: Article査読

15 被引用数 (Scopus)

抄録

The aim of the present study was to determine whether the 2-deoxyglucose uptake of amygdala slices was affected by olfactory bulbectomy. At 7, 14 and 21 days post-lesion, bilateral olfactory bulbectomized rats exhibited a significant increase of 2-deoxyglucose uptake in amygdala slices, but not in the cerebral cortex. In addition, unilateral olfactory bulbectomized rats showed a high uptake of 2-deoxyglucose uptake in the ipsilateral amygdala, but not in the contralateral amygdala. These results suggest that the enhancement of 2-deoxyglucose uptake is related to the hyperexcitability of amygdala neurons following bulbectomy, and that this enhancement may be responsible for the behavioral changes in olfactory bulbectomized rats.

本文言語English
ページ(範囲)147-150
ページ数4
ジャーナルBrain Research
665
1
DOI
出版ステータスPublished - 1994 11 28
外部発表はい

ASJC Scopus subject areas

  • 神経科学(全般)
  • 分子生物学
  • 臨床神経学
  • 発生生物学

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