Fifty-second analysis of oxidative stress markers in human plasma using amide-modified liquid chromatography chip

M. Isokawa, K. Nakanishi, D. H. Yoon, T. Sekiguchi, T. Funatsu, S. Shoji, M. Tsunoda*

*この研究の対応する著者

研究成果: Conference contribution

抄録

This paper reports 50-s liquid chromatography (LC) separation of oxidative stress markers using an amide-modified pillar array column (PAC). The amide modification enables a sufficient retention of highly polar compounds under hydrophilic interaction LC (HILIC) conditions, and five fluorescence-labeled biothiols, i.e., cysteine, homocysteine, glutathione, cysteinylglycine, and N-acetylcysteine, in human plasma could be rapidly separated. Since these biothiols are associated with many diseases, this newly developed method could be a useful tool for the diagnosis or clinical investigation of biothiol-related diseases.

本文言語English
ホスト出版物のタイトル20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
出版社Chemical and Biological Microsystems Society
ページ583-584
ページ数2
ISBN(電子版)9780979806490
出版ステータスPublished - 2016
イベント20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
継続期間: 2016 10 92016 10 13

出版物シリーズ

名前20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
国/地域Ireland
CityDublin
Period16/10/916/10/13

ASJC Scopus subject areas

  • 制御およびシステム工学

フィンガープリント

「Fifty-second analysis of oxidative stress markers in human plasma using amide-modified liquid chromatography chip」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル