Fluorescence microscopic investigation on morphological changes of giant multilamellar vesicles induced by amphiphilic additives

Taro Toyota, Hirotatsu Tsuha, Koji Yamada, Katsuto Takakura, Kenji Yasuda, Tadashi Sugawara*

*この研究の対応する著者

研究成果: Article査読

20 被引用数 (Scopus)

抄録

Adding an artificial bolaamphiphile to a dispersion of giant multilamellar vesicles (GMVs) made of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine (POPC) induced a cup-shaped deformation in GMVs accompanied by partial extrusion of the inner vesicle; thereafter, the deformed vesicles returned to their original shape. On the other hand, when the artificial bolaamphiphile together with a surfactant was added to the vesicular dispersion, these deformation and reformation dynamics were transmitted from the outer membranes in GMVs to the inner membranes until an intact inner vesicle was extruded out of the outer membrane. The microscopic aspects of these processes were investigated using amphiphiles tagged with individual fluorophores.

本文言語English
ページ(範囲)1976-1981
ページ数6
ジャーナルLangmuir
22
5
DOI
出版ステータスPublished - 2006 2 28
外部発表はい

ASJC Scopus subject areas

  • 材料科学(全般)
  • 凝縮系物理学
  • 表面および界面
  • 分光学
  • 電気化学

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