抄録
The neural circuitry comprising the central pattern generator (CPG) that drives feeding behavior in the great pond snail (Lymnaea stagnalis [L., 1758]) has been worked out. Because the feeding behavior undergoes associative learning and long-term memory (LTM) formation, it provides an excellent opportunity to study the causal neuronal mechanisms of these two processes. In this chapter, we explore some of the possible causal neuronal mechanisms of associative learning of conditioned taste aversion (CTA) and its subsequent consolidation processes into LTM in L. stagnalis. In the CTA training procedure, a sucrose solution, which evokes a feeding response, is used as the conditioned stimulus (CS) and a potassium chloride solution, which causes a withdrawal response, is used as the unconditioned stimulus (US). The pairing of the CS-US alters both the feeding response of the snail and the function of a pair of higher order interneurons in the cerebral ganglia. Following the acquisition of CTA, the polysynaptic inhibitory synaptic input from the higher order interneurons onto the feeding CPG neurons is enhanced, resulting in suppression of the feeding response. These changes in synaptic efficacy are thought to constitute a “memory trace” for CTA in L. stagnalis.
| 元の言語 | English |
|---|---|
| ホスト出版物のタイトル | Physiology of Molluscs |
| ホスト出版物のサブタイトル | A Collection of Selected Reviews |
| 出版者 | Apple Academic Press |
| ページ | 43-66 |
| ページ数 | 24 |
| 巻 | 2 |
| ISBN（電子版） | 9781771884099 |
| ISBN（印刷物） | 9781315207483 |
| DOI | |
| 出版物ステータス | Published - 2017 1 1 |
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ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
これを引用
From likes to dislikes : Conditioned taste aversion in the great pond snail (Lymnaea Stagnalis). / Ito, Etsuro; Kojima, S.; Lukowiak, K.; Sakakibara, M.
Physiology of Molluscs: A Collection of Selected Reviews. 巻 2 Apple Academic Press, 2017. p. 43-66.研究成果: Chapter
}
TY - CHAP
T1 - From likes to dislikes
T2 - Conditioned taste aversion in the great pond snail (Lymnaea Stagnalis)
AU - Ito, Etsuro
AU - Kojima, S.
AU - Lukowiak, K.
AU - Sakakibara, M.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - The neural circuitry comprising the central pattern generator (CPG) that drives feeding behavior in the great pond snail (Lymnaea stagnalis [L., 1758]) has been worked out. Because the feeding behavior undergoes associative learning and long-term memory (LTM) formation, it provides an excellent opportunity to study the causal neuronal mechanisms of these two processes. In this chapter, we explore some of the possible causal neuronal mechanisms of associative learning of conditioned taste aversion (CTA) and its subsequent consolidation processes into LTM in L. stagnalis. In the CTA training procedure, a sucrose solution, which evokes a feeding response, is used as the conditioned stimulus (CS) and a potassium chloride solution, which causes a withdrawal response, is used as the unconditioned stimulus (US). The pairing of the CS-US alters both the feeding response of the snail and the function of a pair of higher order interneurons in the cerebral ganglia. Following the acquisition of CTA, the polysynaptic inhibitory synaptic input from the higher order interneurons onto the feeding CPG neurons is enhanced, resulting in suppression of the feeding response. These changes in synaptic efficacy are thought to constitute a “memory trace” for CTA in L. stagnalis.
AB - The neural circuitry comprising the central pattern generator (CPG) that drives feeding behavior in the great pond snail (Lymnaea stagnalis [L., 1758]) has been worked out. Because the feeding behavior undergoes associative learning and long-term memory (LTM) formation, it provides an excellent opportunity to study the causal neuronal mechanisms of these two processes. In this chapter, we explore some of the possible causal neuronal mechanisms of associative learning of conditioned taste aversion (CTA) and its subsequent consolidation processes into LTM in L. stagnalis. In the CTA training procedure, a sucrose solution, which evokes a feeding response, is used as the conditioned stimulus (CS) and a potassium chloride solution, which causes a withdrawal response, is used as the unconditioned stimulus (US). The pairing of the CS-US alters both the feeding response of the snail and the function of a pair of higher order interneurons in the cerebral ganglia. Following the acquisition of CTA, the polysynaptic inhibitory synaptic input from the higher order interneurons onto the feeding CPG neurons is enhanced, resulting in suppression of the feeding response. These changes in synaptic efficacy are thought to constitute a “memory trace” for CTA in L. stagnalis.
KW - Conditioned taste aversion
KW - Feeding
KW - Long-term memory
KW - Lymnaea stagnalis
KW - Withdrawal
UR - http://www.scopus.com/inward/record.url?scp=85056515395&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85056515395&partnerID=8YFLogxK
U2 - 10.1201/9781315207483
DO - 10.1201/9781315207483
M3 - Chapter
AN - SCOPUS:85056515395
SN - 9781315207483
VL - 2
SP - 43
EP - 66
BT - Physiology of Molluscs
PB - Apple Academic Press
ER -