抄録
Functionalization of nanoparticles and immobilization of biomolecules on nanoparticles are important techniques for various applications in biotechnology. For application in the biomedical field, the surface of ultradispersed diamond (UDD) is immobilized with amino-terminated DNA after functionalizing carboxylic or amino group on the UDD surface. The characterized surface of UDD, carboxylated UDD, and aminated UDD were analyzed by DRIFT spectroscopy. In addition, hybridization with Cy-5 labeled target DNA was clearly observed on functionalized UDD by fluorescence microscopy.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 69-75 |
| ページ数 | 7 |
| ジャーナル | Journal of Nanoparticle Research |
| 巻 | 10 |
| 発行部数 | SUPPL. 1 |
| DOI | |
| 出版物ステータス | Published - 2008 12 |
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ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Condensed Matter Physics
- Modelling and Simulation
- Chemistry(all)
- Materials Science(all)
- Bioengineering
これを引用
Functionalization of ultradispersed diamond for DNA detection. / Yang, Jung Hoon; Nakano, Yoshikazu; Murakami, Yasunori; Song, Kwang Soup; Kawarada, Hiroshi.
：: Journal of Nanoparticle Research, 巻 10, 番号 SUPPL. 1, 12.2008, p. 69-75.研究成果: Article
}
TY - JOUR
T1 - Functionalization of ultradispersed diamond for DNA detection
AU - Yang, Jung Hoon
AU - Nakano, Yoshikazu
AU - Murakami, Yasunori
AU - Song, Kwang Soup
AU - Kawarada, Hiroshi
PY - 2008/12
Y1 - 2008/12
N2 - Functionalization of nanoparticles and immobilization of biomolecules on nanoparticles are important techniques for various applications in biotechnology. For application in the biomedical field, the surface of ultradispersed diamond (UDD) is immobilized with amino-terminated DNA after functionalizing carboxylic or amino group on the UDD surface. The characterized surface of UDD, carboxylated UDD, and aminated UDD were analyzed by DRIFT spectroscopy. In addition, hybridization with Cy-5 labeled target DNA was clearly observed on functionalized UDD by fluorescence microscopy.
AB - Functionalization of nanoparticles and immobilization of biomolecules on nanoparticles are important techniques for various applications in biotechnology. For application in the biomedical field, the surface of ultradispersed diamond (UDD) is immobilized with amino-terminated DNA after functionalizing carboxylic or amino group on the UDD surface. The characterized surface of UDD, carboxylated UDD, and aminated UDD were analyzed by DRIFT spectroscopy. In addition, hybridization with Cy-5 labeled target DNA was clearly observed on functionalized UDD by fluorescence microscopy.
KW - Amination
KW - Carboxylation
KW - DNA immobilization
KW - Functionalization
KW - Nanomedicine
KW - Ultradispersed diamond
UR - http://www.scopus.com/inward/record.url?scp=54249125101&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=54249125101&partnerID=8YFLogxK
U2 - 10.1007/s11051-008-9367-2
DO - 10.1007/s11051-008-9367-2
M3 - Article
VL - 10
SP - 69
EP - 75
JO - Journal of Nanoparticle Research
JF - Journal of Nanoparticle Research
SN - 1388-0764
IS - SUPPL. 1
ER -